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Unread 09-10-2013, 02:54 AM
MFS MFS is offline
Join Date: Apr 2013
Posts: 51

I never said it was stronger, merely that the reported kinetics were different. His statement is based on the assumption that "assuming the two have the same pharmacokinetics", so it's circular reasoning in that regard.

In the interest of science, sodium phenolate solutions at low pH (say by the addition of HCl) should protonate (based on pKa) and precipitate out of solution as the solubility of the phenol is quite low I would imagine. Obviously you wouldn't do this at home...
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