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  #1  
Unread 11-20-2017, 01:17 PM
BMWGuinness BMWGuinness is offline
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Default Using CRISPR to cut Myostatin

http://www.ifyoudontknownowyaknow.com/

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How did I do this? CRISPR is some complicated new technology that is really hard! Well, at least that is what the press and media and maybe even some Scientists say. Unfortunately, it's not true. It just took one piece of DNA that contains the Cas9 protein and a guideRNA(gRNA) targeted to the exon 1 of the Myostatin gene and I injected my muscle with it. This DNA then enters some of my cells and both the Cas9 protein and the gRNA would be made by my cells and this molecular complex would target my myostatin gene and cut it. This would lead to Non-Homologous End Joining(NHEJ) and effectively some of the myostatin copies would not work. When myostatin is not working to stop muscle growth, muscles grow.
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  #2  
Unread 11-21-2017, 12:35 AM
BigPecsPeter BigPecsPeter is offline
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Do you believe a word of that?

In future, something like this might be possible for something like myostatin regulation. But now, gene therapy and similar propositions are very much in their infancy.

The only REAL myostatin limiter in current times are those people born with the mutated gene, single copy or double copy. Those people will show greater muscle growth.
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  #3  
Unread 11-21-2017, 12:58 AM
Determinism Determinism is offline
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We always have epicatechin (or cacao extract)...

Although some research claims it inhibits myostatin to some extend, I'm convinced it's yet another way to sell a supplement.

Resources: https://examine.com/supplements/cocoa-extract/
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  #4  
Unread 11-21-2017, 07:55 AM
w1cked w1cked is offline
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Originally Posted by Determinism View Post
We always have epicatechin (or cacao extract)...

Although some research claims it inhibits myostatin to some extend, I'm convinced it's yet another way to sell a supplement.

Resources: https://examine.com/supplements/cocoa-extract/
I'll add that to my 600 mg test maybe I'll get jacked
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  #5  
Unread 11-21-2017, 09:29 AM
lylemcdonald lylemcdonald is offline
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Quote:
Originally Posted by Determinism View Post
We always have epicatechin (or cacao extract)...

Although some research claims it inhibits myostatin to some extend, I'm convinced it's yet another way to sell a supplement.

Resources: https://examine.com/supplements/cocoa-extract/
None of this stuff has or likely will work any more than an previous attempts to to do so.
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  #6  
Unread 11-21-2017, 12:52 PM
Determinism Determinism is offline
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Originally Posted by lylemcdonald View Post
None of this stuff has or likely will work any more than an previous attempts to to do so.
Probably not. If it would work, people would have noticed years ago (since dark chocolate and/or cacoa extract is widely consumed). Nevertheless, still an interesting read.
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  #7  
Unread 11-21-2017, 04:32 PM
lylemcdonald lylemcdonald is offline
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Eating lots of dark chocolate will certainly make you larger

But not in the way I think most are hoping
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