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Unread 04-30-2018, 12:48 PM
PhysiologyIsPhun PhysiologyIsPhun is offline
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Join Date: Aug 2016
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Arrow Yohimbine on keto

Hey all,

As far as I'm aware, the presence of insulin in the bloodstream prevents yohimbine from inhibiting a2 receptors, practically rendering supplementation of yohimbine useless from a fat loss perspective. As such, it is only useful to use yohimbine when one is in a fasted state. I remember reading somewhere on the forums (or possibly in the stubborn fat protocol book) that insulin levels return to near - fasting levels 3-4 hours after an average "meal".

If one is on a ketogenic diet, would insulin levels return to fasted levels quicker after a meal than on a standard isocalorie diet, meaning using yohimbine maybe 1-2 hours after a meal would provide some benefit?

Actually, does a typical keto meal affect insulin levels much at all? Assuming you have around 30g protein or so at a meal, I'd think it would, but I'm curious as to how much it would raise insulin vs a standard isocalorie meal.

From a practical standpoint, I'm just wondering this because I always do my cardio after my lift which is performed after I get off work. Fasting until 7-8pm is just not feasible, and honestly I usually have a terrible lift unless I have some kind of meal an hour or so beforehand. I was thinking practically, I have a high fat/moderate protein meal around 4pm, lift around 5:30-6:30 and take yohimbine sometime during the lift so it's circulating in my bloodstream before I hit the LISS machine of choice afterward. Just wondering if the yohimbine is even useful at that point (would be about 2.5 hours after my last keto meal).


Last edited by PhysiologyIsPhun : 04-30-2018 at 12:51 PM.
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Unread 04-30-2018, 07:42 PM
forsaken3400's Avatar
forsaken3400 forsaken3400 is offline
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Join Date: Jan 2012
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Remember, protein does elicit an insulin response... often even more than a carb rich meal.

I've personally found yohimbine to still be effective 1-2 hours after eating... obviously it's most effective when fasted but a small meal and dosing yohimbine a couple hours after has worked for me.
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Unread 05-01-2018, 02:29 AM
squat squat is offline
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Join Date: Feb 2013
Posts: 758

Well, it's basically only useful for stubborn bodyfat... And it doesn't make much difference, anyway, like most supplements. In most cases, you could lose the fat without it. It's basically for fasted cardio. I've found it gives me shakes and makes me feel awful. Some guys get boners?

insulin is always there. More glucose= more insulin. Carbs= more glucose= more insulin acutely. Protein= some conversion to carbohydrate at not a terrifyingly acute rate.

You know all this, don't you?

Last edited by squat : 05-01-2018 at 02:34 AM.
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Unread 05-01-2018, 06:49 AM
PhysiologyIsPhun PhysiologyIsPhun is offline
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Join Date: Aug 2016
Posts: 275

Anecdotally, I've found yohimbine seems to help substantially when combined with fasted cardio once I start to get close to that 10% range. Could be just because of the fasted cardio I suppose, but either way I definitely notice a pretty big difference. My problem is I have a really hard time fitting in morning fasted cardio with my current schedule. And a 4 hour mid-day fast is rather difficult as well considering I practice intermittent fasting to control calorie intake. Thats why I'm curious if yohimbine would still be effective using the way I described in the OP. I suppose if it's not, I can suck it up and start getting up at 5am to do my fasted cardio like a good little bodybuilder.

Oh and the boner thing. Yeah, that's definitely real.
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