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#11
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![]() Got 'em, thanks.
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#12
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![]() "Another conseqhttp://www.bodyrecomposition.com/wp-admin/post.php?action=edit&post=3988uence"
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#13
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![]() That was weird
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#15
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![]() total energy expenditure may still be lower than expected due to a decreased TEF And reduced overall daily activity.
lowercase I’d note that bigger individual burn more calories during activity by dint of being larger individuals |
#16
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![]() Lyle - I really love this series. I can relate to it so much because of my own history of weight issues. I tried for years to "exercise it off" and felt like a complete failure because it didn't work.
There are a lot of "professional trainers" out there that sure need to read this. |
#17
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![]() Got 'em thanks.
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#18
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![]() Just a comment to say how much I enjoyed this article,
I was formerly very obese so it is always interesting to read about this kind of stuff from a personal, reflective perspective. For those interested, it seems that allelic variations in the ADRB-2 gene (beta 2 adrenergic receptor) are associated with reduced fat burning during exercise and this could manifest itself as an elevated RER, as Lyle points out. |
#19
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![]() There's a host of genetic variations that have been implicated in obesity. Determining what's causing what and what's present is at the current time difficult. But I suspect that, going forwards, it will lead to far more individualized obesity treatments where genetic testing (or hormonal testing or nutragenomics) will allow much more specific prescription to target the pathways/whatever that are the problem. But it's years down the road.
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#20
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![]() I suspect, as you mention Lyle, that we are many years away from narrowing things down. And I suspect that many researchers (at least the ones that I am aware of at the time of writing this post anyway - excuse me if I am wrong) are identifying aspects in isolation primarily and how these interact as a larger whole, and in the context of environment, is another ballgame entirely I would imagine.
Interestingly, I had a genetic profile done on myself for free a while back and it confirmed some observations I had made of myself during lab tests, namely elevated RER during submaximal exercise tests, poor lactate tolerance and clearance rates, etc. I am the genetic craphole it seems. Still, the effects of a well constructed diet and exercise have paid dividends to me. |
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