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  #1  
Unread 03-03-2018, 11:17 AM
holly70 holly70 is offline
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Location: Michigan
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Default 5 Types of Diabetes

Maybe more, but this particular study has broken it into 5:

Quote:
Cluster 1 - severe autoimmune diabetes is broadly the same as the classical type 1 - it hit people when they were young, seemingly healthy and an immune disease left them unable to produce insulin

Cluster 2 - severe insulin-deficient diabetes patients initially looked very similar to those in cluster 1 - they were young, had a healthy weight and struggled to make insulin, but the immune system was not at fault

Cluster 3 - severe insulin-resistant diabetes patients were generally overweight and making insulin but their body was no longer responding to it

Cluster 4 - mild obesity-related diabetes was mainly seen in people who were very overweight but metabolically much closer to normal than those in cluster 3

Cluster 5 - mild age-related diabetes patients developed symptoms when they were significantly older than in other groups and their disease tended to be milder
Quote:
We identified five replicable clusters of patients with diabetes, which had significantly different patient characteristics and risk of diabetic complications. In particular, individuals in cluster 3 (most resistant to insulin) had significantly higher risk of diabetic kidney disease than individuals in clusters 4 and 5, but had been prescribed similar diabetes treatment. Cluster 2 (insulin deficient) had the highest risk of retinopathy. In support of the clustering, genetic associations in the clusters differed from those seen in traditional type 2 diabetes.
Only 2 mention overweight/obesity specifically. No info on the prevalence they found. Could be in the actual journal article.

http://www.thelancet.com/journals/la...xt?elsca1=tlpr
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  #2  
Unread 03-04-2018, 12:06 PM
lylemcdonald lylemcdonald is offline
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Default

1 and 2 are in the youth.

3/4 are weight gain related

5 is age related and usually weight is gained with age
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