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  #1  
Unread 08-07-2017, 08:05 PM
holly70 holly70 is offline
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Default Hope for chubby old ladies?

Posted to my old lady FB group.

Mouse study found that dosing mice that had surgically had their ovaries removed with an antibody that blocked FSH appeared to:

-avoid developing fat filled bone marrow
-lost large amounts of fat

Further research theorized that the increased metabolic rate was due to conversion of white fat to brown fat.

https://mobile.nytimes.com/2017/08/0...m.facebook.com

Just rats so far, but seems like a human trial is being planned.
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  #2  
Unread 08-08-2017, 07:47 AM
BigPecsPeter BigPecsPeter is offline
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Lovely.
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  #3  
Unread 08-08-2017, 08:42 AM
ssg10587 ssg10587 is offline
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Don't ovaries play a key role in hormone production for women? Seems like it could cause trouble. What would happen to hormones levels for these women? From the study, sounds like estrogen drastically drops...then what? You're left with low levels of estrogen and test?

Also going out on a limb and saying surgery for this would be rather pricey and not too practical.

Little bit of a rant but I'm blown away by the extent humanity goes to just to not have to eat less and diet right Seems like always looking for some magical bullet to make people not have to put in the work.
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  #4  
Unread 08-08-2017, 09:54 AM
BigPecsPeter BigPecsPeter is offline
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Quote:
Originally Posted by ssg10587 View Post
Don't ovaries play a key role in hormone production for women? Seems like it could cause trouble. What would happen to hormones levels for these women? From the study, sounds like estrogen drastically drops...then what? You're left with low levels of estrogen and test?

Also going out on a limb and saying surgery for this would be rather pricey and not too practical.

Little bit of a rant but I'm blown away by the extent humanity goes to just to not have to eat less and diet right Seems like always looking for some magical bullet to make people not have to put in the work.
It's work, whatever way you look at it. People try to make things easier and end up making things harder and more complicated
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  #5  
Unread 08-08-2017, 04:26 PM
w1cked w1cked is offline
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Well there's always lipo
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  #6  
Unread 08-09-2017, 06:58 AM
holly70 holly70 is offline
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Yeah, I don't think they are planning to surgically remove womens' ovaries to help them lose weight.

I took it more as, hey, we notice that menopause causes these changes in women (metabolism, fat pattern) and now we think that is because of FSH, so maybe we can give them a pill to block that.

And when they tried it in mice they found an unexpected level of fat loss.

Not likely to be helpful to the general population, or even old ladies that really just eat too much and don't move enough vs. "average".

It might even just lead to a general reformulation of HRT therapy.
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  #7  
Unread 08-09-2017, 10:10 AM
BigPecsPeter BigPecsPeter is offline
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Yeah. Or people could just stop being so bloody vain and accept the aging process. Body's going to sag and get droopy and horrid. And? By that point you should probably have enough accumulated wisdom to realise it doesn't really matter
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