BodyRecomposition Support Forums  

Go Back   BodyRecomposition Support Forums > Miscellaneous > Miscellaneous Discussion
Register FAQ Members List Calendar Search Today's Posts Mark Forums Read

Reply
Thread Tools Display Modes
  #1  
Unread 09-29-2017, 03:56 PM
holly70 holly70 is offline
Senior Member
 
Join Date: Mar 2016
Location: Michigan
Posts: 251
Default Belly Fat May Be Affected By Enzyme Manipulation In Older Adults

As I read it a newly discovered macrophage appears to prevent older adults from burning belly fat. MAOA seems to restore normal fat metabolism; at least in the older mice.

Quote:
The researchers found that when they lowered a specific receptor that controls inflammation, the NLRP3 inflammasome, in aged macrophages, the catecholamines could act to induce fat breakdown, similar to that of young mice.

"The key finding is that the immune cells talk to the nervous system to control metabolism," said Dixit.

In further experiments, the researchers blocked an enzyme that is increased in aged macrophages, restoring normal fat metabolism in older mice. Dixit noted that this enzyme, monoamine oxidase-A or MAOA, is inhibited by existing drugs in the treatment of depression. "Theoretically one could repurpose these MAOA inhibitor drugs to improve metabolism in aged individuals," he said. But he also cautioned that more research is needed to specifically target these drugs to belly fat and to test the safety of this approach.
https://medicalxpress.com/news/2017-...ign=story-tabs

I browse phys.org sometimes when I'm bored.
Reply With Quote
  #2  
Unread 09-29-2017, 07:56 PM
lylemcdonald lylemcdonald is offline
Administrator
 
Join Date: Dec 2015
Posts: 881
Default

Mice, who cares
Reply With Quote
Reply


Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump


All times are GMT -6. The time now is 10:10 PM.


Powered by vBulletin® Version 3.6.8
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.